The IL34 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated from Bioss Inc. is a Rabbit Polyclonal antibody to IL34, and Interleukin 34. This antibody recognizes Mouse antigen. The IL34 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated has been validated for the following applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry - fixed, and Immunohistochemistry - frozen.
Description
Cytokine that promotes the proliferation, survival and differentiation of monocytes and macrophages. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, and in the regulation of bone resorption. Signaling via CSF1R and its downstream effectors stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1 (By similarity)